Document And Entity Information Dividend yield us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo 2026 Note To Financial Statement Details Textual Significant Accounting Policies us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths 2025 Loan Agreement [Member] Represents the loan agreement. Note 2 - Summary of Significant Accounting Policies us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo 2026 Note 3 - Fair Value of Financial Instruments Risk-free interest rate Clinical trial fees and costs Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to clinical trial fees and costs. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Note 4 - Balance Sheet Components Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block] Note 6 - Stockholders' Equity and Stock-based Compensation Note 8 - Commitments and Contingencies us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths 2025 Note 2 - Summary of Significant Accounting Policies - Warrant Accrual Activity (Details) plse_NumberOfSharesPerUnitIssued Number of Shares Per Unit Issued (in shares) Number of shares of stock issued or issuable for each unit. Note 2 - Summary of Significant Accounting Policies - Antidilutive Securities (Details) plse_NumberOfWarrantsPerUnit Number of Warrants Per Unit (in shares) Number of warrants issued or issuable for each unit. Note 3 - Investments and Fair Value of Financial Instruments - Financial Assets Measured on a Recurring Basis (Details) Note 4 - Balance Sheet Components - Property and Equipment, Net (Details) Note 4 - Balance Sheet Components - Intangible Assets, Net (Details) Note 4 - Balance Sheet Components - Schedule of Amortization of Intangible Assets (Details) Expected volatility us-gaap_ShareBasedCompensation Stock-based compensation Note 4 - Balance Sheet Components - Accrued Expenses (Details) Other assets Note 6 - Stockholders' Equity and Stock-based Compensation - Summary of Stock Option Activity (Details) us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear 2024 (remaining 9 months) us-gaap_LiabilitiesCurrent Total current liabilities plse_ClassOfWarrantOrRightExerciseConsecutiveTradingDays Class of Warrant or Right, Exercise, Consecutive Trading Days (Day) The consecutive trading days for exercise of warrant or right. Note 6 - Stockholders' Equity and Stock-based Compensation - Summary of Time-based Option Activity (Details) plse_ClassOfWarrantOrRightExercisedDuringPeriod Class of Warrant or Right, Exercised During Period (in shares) The number of warrants or rights exercised during period. Note 6 - Stockholders' Equity and Stock-based Compensation - Summary of Performance Option Activity (Details) us-gaap_FiniteLivedIntangibleAssetUsefulLife Finite-Lived Intangible Asset, Useful Life (Year) Note 6 - Stockholders' Equity and Stock-based Compensation - Summary of Market-based Option Activity (Details) Note 6 - Stockholders' Equity and Stock-based Compensation - Option Assumptions (Details) Expected term in years (Year) Earnings Per Share, Policy [Policy Text Block] Rights Offering Warrants [Member] Represents Rights Offering Warrants. Note 6 - Stockholders' Equity and Stock-based Compensation - ESPP Assumptions (Details) Note 6 - Stockholders' Equity and Stock-based Compensation - Stock-based Compensation Expense by Recorded Location (Details) us-gaap_BusinessCombinationConsiderationTransferred1 Business Combination, Consideration Transferred, Total plse_ClassOfWarrantOrRightPeriodOfWrittenNoticeForExercise Class of Warrant or Right, Period of Written Notice for Exercise (Day) The period of written notice for warrants or rights to be exercised. Note 6 - Stockholders' Equity and Stock-based Compensation - Stock-based Compensation Expense by Type (Details) plse_ClassOfWarrantOrRightPercentageRequiredForRedemption Class of Warrant or Right, Percentage Required for Redemption The percentage required for redemption of warrant or right. Note 8 - Commitments and Contingencies - Information Related to Right-of-use Assets and Lease Liabilities (Details) plse_IncreaseInSharesAvailableForIssuanceThresholdOfCommonStockOutstandingPercent Increase in Shares Available for Issuance, Threshold of Common Stock Outstanding, Percent Percentage of threshold of common stock outstanding for increase in shares available for issuance. Notes To Financial Statements plse_IncreaseInSharesAvailableForIssuanceThresholdOfCommonStockOutstandingNumberOfShares Increase in Shares Available for Issuance, Threshold of Common Stock Outstanding, Number of Shares (in shares) The number of shares threshold for increase in shares available for issuance. Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Notes To Financial Statements [Abstract] The 2017 Inducement Equity Incentive Plan [Member] Represents the 2017 Inducement Equity Incentive Plan. plse_ClassOfWarrantsOrRightsRedemptionPricePerShare Class of Warrants or Rights, Redemption Price Per Share (in dollars per share) Per share redemption price of warrants or rights. Total assets measured at fair value Total assets measured at fair value Share-Based Payment Arrangement, Option, Activity [Table Text Block] us-gaap_NumberOfBusinessesAcquired Number of Businesses Acquired The 2017 Plan [Member] Represents the 2017 plan. The 2017 Employee Stock Purchase Plan [Member] Represents the 2017 Employee Stock Purchase Plan. Schedule of Finite-Lived Intangible Assets [Table Text Block] Time-based Options [Member] Represents time-based options. plse_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsGrantsInPeriodIntrinsicValue Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Intrinsic Value Amount of accumulated difference between fair value of underlying shares on dates of grant and exercise price on options granted. us-gaap_LesseeOperatingLeaseTermOfContract Lessee, Operating Lease, Term of Contract (Year) Performance Options [Member] Represents performance options. Depreciation Depreciation Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Old Dominion University Research Foundation [Member] Represents Old Dominion University Research Foundation. us-gaap_SharesIssuedPricePerShare Shares Issued, Price Per Share (in dollars per share) Sponsored Research Agreement SRA [Member] Represents sponsored research agreement (SRA). The 2015 Plan, 2017 Plan and Inducement Plan [Member] Represents the 2015 Plan, 2017 Plan and Inducement Plan. us-gaap_AssetsCurrent Total current assets Options exercisable, weighted average remaining life (Year) Cash and Cash equivalents Share-Based Payment Arrangement [Policy Text Block] Employee Stock Purchase Plan Award [Member] Represents award under ESPP. Options exercisable, number of shares (in shares) Options balances, weighted average remaining life (Year) plse_DirectorsAndOfficersLiabilityInsurancePeriod Directors and Officers Liability Insurance, Period (Year) Period of liability insurance for directors and officers. Interest income (expense), net Common stock, $0.001 par value; authorized – 500,000 shares; issued and outstanding – 55,225 shares and 55,144 shares at March 31, 2024 and December 31, 2023 respectively Corporate Headquarters in Hayward, California [Member] Represents corporate headquarters located in Hayward, California. Expansion Premises 1 [Member] Represents Expansion Premises 1. Adjustments to reconcile net loss to net cash used in operating activities: Expansion Premises 2 [Member] Represents Expansion Premises 2. us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice Options balances, weighted average exercise price (in dollars per share) Options balances, weighted average exercise price (in dollars per share) Common stock, shares authorized (in shares) Letter Agreement [Member] Represents Letter Agreement. Options canceled, weighted average exercise price (in dollars per share) Common stock, shares issued (in shares) Options expired, weighted average exercise price (in dollars per share) Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share (in dollars per share) Options granted, weighted average exercise price (in dollars per share) Options exercised, weighted average exercise price (in dollars per share) Accrued expenses Accrued Liabilities, Current Total accrued expenses Schedule of Information Related to Right-of-use Assets and Lease Liabilities [Table Text Block] Tabular disclosure for all information related to right-of-use assets and lease liabilities. Standard Product Warranty, Policy [Policy Text Block] Compensation expense Statistical Measurement [Domain] Cash paid for operating lease liabilities us-gaap_OperatingLeasePayments Maximum [Member] Minimum [Member] Accounts payable us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber Options balances, number of shares (in shares) Options balances, number of shares (in shares) Statistical Measurement [Axis] us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod Options expired, number of shares (in shares) Preferred stock, $0.001 par value; authorized – 50,000 shares; no shares issued and outstanding Other us-gaap_OtherAccruedLiabilitiesCurrent Preferred stock, shares issued (in shares) us-gaap_PolicyTextBlockAbstract Accounting Policies Property, Plant and Equipment [Table Text Block] Preferred stock, shares authorized (in shares) 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of Shares Authorized (in shares) Fair Value, Inputs, Level 1 [Member] Fair Value, Inputs, Level 2 [Member] us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1 Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period (Year) us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Fair Value Hierarchy and NAV [Axis] Goodwill Disclosure [Text Block] Current liabilities: Supplemental Balance Sheet Disclosures [Text Block] Vesting [Axis] Vesting [Domain] Lease liabilities Share-Based Payment Arrangement, Tranche One [Member] us-gaap_Assets Total assets Software and Software Development Costs [Member] Plan Name [Axis] Plan Name [Domain] Construction in Progress [Member] us-gaap_OperatingLeaseExpense Operating Lease, Expense Cash flows from operating activities: Statement [Line Items] 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Award Type [Axis] us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization Less: Accumulated amortization Intangible assets, net Total us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Private Placement [Member] us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect Net decrease in cash and cash equivalents Acquired patents and licenses us-gaap_NetCashProvidedByUsedInFinancingActivities Net cash provided by (used in) financing activities us-gaap_Liabilities Total liabilities Commitments and contingencies (Note 8) Sale of Stock [Axis] Sale of Stock [Domain] us-gaap_OperatingIncomeLoss Loss from operations us-gaap_NetCashProvidedByUsedInOperatingActivities Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Share-Based Payment Arrangement, Option [Member] Other income (expense): us-gaap_NetCashProvidedByUsedInInvestingActivities Net cash used in investing activities Warrant [Member] Prepaid expenses and other current assets Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Commitments and Contingencies Disclosure [Text Block] us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment Less: Accumulated depreciation and amortization Property and equipment, net Total property and equipment, net Goodwill Goodwill, Ending Balance us-gaap_InterestPayableCurrentAndNoncurrent Interest Payable Property and equipment, gross Costs and Expenses Total cost and expenses Cost and expenses: Cash flows from investing activities: Proceeds from issuance of common stock under employee stock purchase plan Proceeds from exercises of warrants Proceeds from Warrant Exercises Net loss per share: Retained Earnings [Member] Total revenues Proceeds from exercises of stock options us-gaap_ProceedsFromIssuanceOfCommonStock Proceeds from Issuance of Common Stock Title and Position [Domain] Title and Position [Axis] Income (Loss) from Continuing Operations, Net of Tax, Including Portion Attributable to Noncontrolling Interest us-gaap_RelatedPartyTransactionAmountsOfTransaction Related Party Transaction, Amounts of Transaction Additional Paid-in Capital [Member] Common Stock [Member] Related Party Transactions Disclosure [Text Block] us-gaap_IncomeTaxExpenseBenefit Income tax benefit us-gaap_IncreaseDecreaseInAccruedLiabilities Accrued expenses Equity Components [Axis] Equity Component [Domain] us-gaap_IncreaseDecreaseInAccountsPayable Accounts payable us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1 Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) Class of Warrant or Right [Axis] Class of Warrant or Right [Domain] us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight Class of Warrant or Right, Number of Securities Called by Each Warrant or Right (in shares) us-gaap_ClassOfWarrantOrRightOutstanding Class of Warrant or Right, Outstanding (in shares) us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest Loss from operations, before income taxes us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) General and administrative us-gaap_DebtInstrumentIncreaseAccruedInterest Debt Instrument, Increase, Accrued Interest us-gaap_DebtInstrumentDecreaseForgiveness Debt Instrument, Decrease, Forgiveness Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Accrued interest on related party note payable Total stock-based compensation expense us-gaap_RepaymentsOfRelatedPartyDebt Payments made on related party note Document Quarterly Report Amendment Flag Entity Incorporation, State or Country Code General and Administrative Expense [Member] Accounting Policies [Abstract] Significant Accounting Policies [Text Block] us-gaap_ComprehensiveIncomeNetOfTax Comprehensive loss Document Transition Report City Area Code Basis of Accounting, Policy [Policy Text Block] Use of Estimates, Policy [Policy Text Block] New Accounting Pronouncements, Policy [Policy Text Block] Entity Interactive Data Current us-gaap_IncreaseDecreaseInContractWithCustomerLiability Deferred revenue us-gaap_SharesOutstanding Balance (in shares) Balance (in shares) Security Exchange Name Common stock, shares outstanding (in shares) Preferred stock, shares outstanding (in shares) Title of 12(b) Security Current Fiscal Year End Date us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets Prepaid expenses and other current assets Research and Development Expense [Member] Weighted-average discount rate Document Fiscal Period Focus Document Fiscal Year Focus Consolidation, Policy [Policy Text Block] Document Period End Date Statement of Income Location, Balance [Axis] Statement of Income Location, Balance [Domain] Weighted-average remaining lease term (Year) Entity File Number Entity Emerging Growth Company us-gaap_DebtInstrumentFaceAmount Debt Instrument, Face Amount Document Type Entity Small Business Entity Shell Company Document Information [Line Items] Document Information [Table] us-gaap_InvestmentOwnedPercentOfNetAssets Investment Owned, Percent of Net Assets us-gaap_AreaOfRealEstateProperty Area of Real Estate Property (Acre) Entity Filer Category Debt Instrument [Axis] Entity Current Reporting Status Debt Instrument, Name [Domain] us-gaap_RestructuringCharges Restructuring Charges Name of Property [Axis] Name of Property [Domain] us-gaap_IncreaseDecreaseInOtherReceivables Other receivables us-gaap_GoodwillImpairmentLoss Goodwill, Impairment Loss Antidilutive securities (in shares) Stock-based compensation expense Entity Tax Identification Number Entity Central Index Key Entity Registrant Name Entity [Domain] Market-based Options [Member] Represents market-based options. Legal Entity [Axis] Performance-based Options [Member] Represents performance based options. Statement [Table] Entity Address, Address Line One Statement of Financial Position [Abstract] Time-based and Performance Options [Member] Represents time-based and performance options. Weighted average shares used to compute net loss per common share — basic and diluted (in shares) us-gaap_RestructuringIncurredCostStatementOfIncomeOrComprehensiveIncomeExtensibleEnumeration Restructuring Charges, Statement of Income or Comprehensive Income [Extensible Enumeration] ecd_NonRule10b51ArrTrmntdFlag Non-Rule 10b5-1 Arrangement Terminated [Flag] Amortization of intangible assets Less: Adjustment for inventory at cost and excessive and obsolete inventory Represents the adjustment for inventory at cost. Entity Address, City or Town ecd_Rule10b51ArrTrmntdFlag Rule 10b5-1 Arrangement Terminated [Flag] ecd_Rule10b51ArrAdoptedFlag Rule 10b5-1 Arrangement Adopted [Flag] Entity Address, Postal Zip Code Business Acquisition [Axis] Basic and diluted net loss per share (in dollars per share) Entity Address, State or Province Business Acquisition, Acquiree [Domain] ecd_NonRule10b51ArrAdoptedFlag Non-Rule 10b5-1 Arrangement Adopted [Flag] Series of Individually Immaterial Business Acquisitions [Member] Material Terms of Trading Arrangement [Text Block] Statement of Cash Flows [Abstract] Entity Common Stock, Shares Outstanding Lease Contractual Term [Domain] Statement of Stockholders' Equity [Abstract] Lease Contractual Term [Axis] Income Statement [Abstract] Schedule of Accrued Liabilities [Table Text Block] plse_EquityOfferingUnitsSaleOfUnits Equity Offering, Units, Sale of Units (in shares) Total units issued during the year. Trading Symbol us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated Restructuring and Related Cost, Number of Positions Eliminated plse_DebtInstrumentQuarterlyInterestRate Debt Instrument Quarterly Interest Rate Debt instrument, quarterly interest rate Robert W. Duggan [Member] Represents Robert W. Duggan Two Thousand Twenty Two Loan Agreement [Member] Represents the 2022 Loan Agreement Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Issuance of common stock under employee stock purchase plan (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans (in shares) Local Phone Number Issuance of common stock upon exercise of stock options (in shares) Options exercised, number of shares (in shares) us-gaap_TableTextBlock Notes Tables Issuance of common stock under employee stock purchase plan Issuance of common stock upon exercise of stock options Related and Nonrelated Parties [Axis] Type of Restructuring [Domain] Related and Nonrelated Parties [Domain] Employee Severance [Member] Restructuring and Related Activities Disclosure [Text Block] Fair Value, Assets Measured on Recurring Basis [Table Text Block] Restructuring Type [Axis] Cash flows from financing activities: Options granted, number of shares (in shares) us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod Options canceled, number of shares (in shares) us-gaap_StockIssuedDuringPeriodSharesNewIssues Stock Issued During Period, Shares, New Issues (in shares) us-gaap_LiabilitiesAndStockholdersEquity Total liabilities and stockholders’ equity Related Party Transaction [Axis] Related Party Transaction [Domain] Accumulated deficit Retained Earnings (Accumulated Deficit) Research and development Research and Development Expense Accumulated other comprehensive income (loss) Money Market Funds [Member] Research, Development, and Computer Software Disclosure [Text Block] Cash and Cash Equivalents [Axis] us-gaap_InterestExpense Interest Expense Cash and Cash Equivalents [Domain] Issuance of shares upon exercise of warrants Value of stock issued during the period for the exercise of warrants. Changes in operating assets and liabilities: us-gaap_StockholdersEquity Total stockholders’ equity Balance Balance Rights Offering [Member] Represents rights offering. us-gaap_DisclosureTextBlockAbstract Notes to Financial Statements plse_IncreaseDecreaseInOperatingLeaseRightOfUseAsset Right-of-use assets Amount of increase (decrease) in operating lease right of use asset. Subsequent Event [Member] Non-current operating lease liabilities Lease liability, less current portion Issuance of shares upon exercise of warrants (in shares) Number of shares issued during the period for the exercise of warrants. Class of Stock [Axis] Total lease liabilities us-gaap_OperatingLeaseLiability plse_LesseeOperatingLeaseLiabilityToBePaidAfterYearThree Thereafter Amount of lessee's undiscounted obligation for lease payment for operating lease due after third fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). Subsequent Event Type [Axis] plse_NumberOfWarrantsInEachUnit Number of Warrants in Each Unit (in shares) Represents number of warrants in each unit. Current operating lease liabilities Lease liability, current plse_ImpairmentOfMarketableSecurities Impairment of Marketable Securities Amount of impairment of marketable securities. plse_EquityOfferingUnitsMaximumAmountAuthorized Equity Offering, Units, Maximum Amount Authorized Maximum amount authorized for units issued under equity offering. Subsequent Event Type [Domain] Going Concern [Policy Text Block] Disclosure of accounting policy for going concern. Subsequent Events [Text Block] Options exercisable, weighted average exercise price (in dollars per share) Right-of-use assets Laboratory Equipment [Member] Represents laboratory equipment. us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue Total lease payments Acquired Patents and Licenses [Member] Represents acquired patents and licenses. us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount Less imputed interest plse_ClassOfWarransOrRightExercisePricePercentageOfSubscriptionPriceForUnits Class of Warrans or Right, Exercise Price, Percentage of Subscription Price for Units Amount of exercise price of warrants as percentage of subscription price for units. us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree 2027 plse_SubscriptionPricePerUnitMaximumBenchmark Subscription Price Per Unit, Maximum Benchmark (in dollars per share) Maximum amount of subscription price per unit. us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear 2024 (remaining 9 months)