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  <xsd:element abstract="true" id="plse_PerformancebasedAndMarketbasedOptionsMember" name="PerformancebasedAndMarketbasedOptionsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_PerformancebasedOptionsMember" name="PerformancebasedOptionsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_PolicyTable" name="PolicyTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element id="plse_ProceedsFromIssuanceOfCommonStockAndWarrants" name="ProceedsFromIssuanceOfCommonStockAndWarrants" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="plse_RightOfferingDeemedDividend" name="RightOfferingDeemedDividend" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_RightsOfferingMember" name="RightsOfferingMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="plse_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesModified" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesModified" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration"/>
  <xsd:element id="plse_StockIssuedDuringPeriodSharesExerciseOfWarrants" name="StockIssuedDuringPeriodSharesExerciseOfWarrants" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration"/>
  <xsd:element id="plse_StockIssuedDuringPeriodValueExerciseOfWarrants" name="StockIssuedDuringPeriodValueExerciseOfWarrants" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="plse_SubscriptionRightNumberOfUnits" name="SubscriptionRightNumberOfUnits" nillable="true" substitutionGroup="xbrli:item" type="xbrli:decimalItemType" xbrli:periodType="instant"/>
  <xsd:element abstract="true" id="plse_The2015Plan2017PlanAndInducementPlanMember" name="The2015Plan2017PlanAndInducementPlanMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_The2017EmployeeStockPurchasePlanMember" name="The2017EmployeeStockPurchasePlanMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_The2017InducementEquityIncentivePlanMember" name="The2017InducementEquityIncentivePlanMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_The2017PlanMember" name="The2017PlanMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_The2018PlanMember" name="The2018PlanMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_The2024RightOfferingMember" name="The2024RightOfferingMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_TimebasedAndPerformanceOptionsMember" name="TimebasedAndPerformanceOptionsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_TimebasedOptionsMember" name="TimebasedOptionsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="plse_UnpaidWarrantIssuanceCosts" name="UnpaidWarrantIssuanceCosts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_VestingOfFirstHalfMember" name="VestingOfFirstHalfMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_VestingOfSecondHalfMember" name="VestingOfSecondHalfMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_WarrantsIssuedIn2024RightsOfferingMember" name="WarrantsIssuedIn2024RightsOfferingMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-10-stockbased-compensation-option-assumptions-details" name="statement-statement-note-10-stockbased-compensation-option-assumptions-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-10-stockbased-compensation-stock-option-activity-details" name="statement-statement-note-10-stockbased-compensation-stock-option-activity-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-10-stockbased-compensation-stockbased-compensation-expense-details" name="statement-statement-note-10-stockbased-compensation-stockbased-compensation-expense-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-10-stockbased-compensation-tables" name="statement-statement-note-10-stockbased-compensation-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-12-income-taxes-deferred-tax-asset-liability-details" name="statement-statement-note-12-income-taxes-deferred-tax-asset-liability-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-12-income-taxes-reconciliation-of-income-tax-rate-details" name="statement-statement-note-12-income-taxes-reconciliation-of-income-tax-rate-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-12-income-taxes-reconciliation-of-unrecognized-tax-benefit-details" name="statement-statement-note-12-income-taxes-reconciliation-of-unrecognized-tax-benefit-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-12-income-taxes-tables" name="statement-statement-note-12-income-taxes-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-13-net-loss-per-share-antidilutive-securities-details" name="statement-statement-note-13-net-loss-per-share-antidilutive-securities-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-13-net-loss-per-share-tables" name="statement-statement-note-13-net-loss-per-share-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-14-segment-reporting-reconciliation-of-net-loss-details" name="statement-statement-note-14-segment-reporting-reconciliation-of-net-loss-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-14-segment-reporting-tables" name="statement-statement-note-14-segment-reporting-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-3-fair-value-measurement-financial-assets-measured-on-a-recurring-basis-details" name="statement-statement-note-3-fair-value-measurement-financial-assets-measured-on-a-recurring-basis-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-3-fair-value-measurement-tables" name="statement-statement-note-3-fair-value-measurement-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-4-property-and-equipment-net-property-and-equipment-net-details" name="statement-statement-note-4-property-and-equipment-net-property-and-equipment-net-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-4-property-and-equipment-net-tables" name="statement-statement-note-4-property-and-equipment-net-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-5-intangible-assets-net-details" name="statement-statement-note-5-intangible-assets-net-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-5-intangible-assets-net-schedule-of-amortization-of-intangible-assets-details" name="statement-statement-note-5-intangible-assets-net-schedule-of-amortization-of-intangible-assets-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-5-intangible-assets-net-tables" name="statement-statement-note-5-intangible-assets-net-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-6-accrued-liabilities-accrued-expenses-details" name="statement-statement-note-6-accrued-liabilities-accrued-expenses-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-6-accrued-liabilities-tables" name="statement-statement-note-6-accrued-liabilities-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-8-leases-lease-costs-details" name="statement-statement-note-8-leases-lease-costs-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-8-leases-maturities-of-lease-liabilities-details" name="statement-statement-note-8-leases-maturities-of-lease-liabilities-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-8-leases-remaining-lease-term-and-discount-rate-details" name="statement-statement-note-8-leases-remaining-lease-term-and-discount-rate-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-8-leases-tables" name="statement-statement-note-8-leases-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-9-stockholders-equity-tables" name="statement-statement-note-9-stockholders-equity-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-note-9-stockholders-equity-warrant-activity-details" name="statement-statement-note-9-stockholders-equity-warrant-activity-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="plse_statement-statement-significant-accounting-policies-policies" name="statement-statement-significant-accounting-policies-policies" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
</xsd:schema>
